The Church of San Bartolomé is located in the Barrio de San Bartolomé neighbourhood, formerly the Jewish Quarter, in Seville. After the expulsion of the Jews, the synagogue here passed into the hands of the canonry and it was converted into a church. In the 18th century the original building was demolished and a new church was built that would be inaugurated in 1800.
The exterior of the temple is very simple and features a main doorway and a tower, which is unadorned and this is rare in the city's the towers.
The interior of the Church of San Bartolomé is in the form of a Latin cross, it has three naves separated by pillars with a choir at their foot. Over the central nave there is a vault and there are groin vaults over the lateral naves, the walls are painted white. The Main Altarpiece is in the 18th-century Neoclassical style.
A main feature is the Chapel of Nuestra Señora de la Alegría, enclosed behind a grille, it is the see of the Patron Saint of the popular Barrio de San Bartolomé neighbourhood. The image of the Virgin is from the 16th century, attributed to Roque Balduque and is of great devotion in the city. It is taken out on procession in the month of May. The walls and the vault are decorated with fresco paintings.
In the baptism chapel, there are two plaques in memory of the Venerable Don Miguel Mañara and San Manuel González García who were baptised in this temple.