Espiel is located in the north of the province, in the Guadiato Valley, among mountainous scenery consisting largely of holm oaks and undergrowth. The River Guadiato flows through the village and is the natural hub of the whole region, determining its ecological makeup and creating Puente Nuevo Reservoir, a place of great scenic and ecological interest.

The village is a labyrinth of steep, narrow streets, alleys and passages filled with white houses, the highlight of which is St. Sebastian"s Church.